Research programs

Towards precision medicine

My research connects five threads that most fields keep separate. The first is tumour immunology: the conversation between a cancer and the immune system. The second is spatial biology. I image tissue to see where immune cells sit, how the tumour's scaffold is built, and what that predicts. The third is AI and digital pathology. I build the analysis infrastructure myself, so that a pathology image can become a readout a clinician can trust. The fourth is the clinic, where I design the correlative science that turns tissue from clinical studies into evidence about which patients a treatment will help. The fifth is drug discovery, where I contribute the disease biology to an industry program developing a small-molecule inhibitor for cancer. Each thread informs the others. Better imaging trains better AI. Better biology points to better targets. The clinic tells us which questions matter.

Dr. Amr H. Allam in the laboratory.