My research connects five threads that most fields keep separate. It starts with tumour immunology — understanding the conversation between cancer and the immune system. I make that conversation visible through spatial biology, imaging tissue to see where immune cells sit, how the tumour's scaffold is built, and what that predicts. I build the AI and digital pathology tools that turn those images into decisions a clinician can trust — not as a user of existing platforms, but as someone who has built the analysis infrastructure from the ground up. I carry the biology forward into candidate medicines through translational drug discovery. And I test these ideas in the clinic — the MODULATE Trial is a national programme that applies these principles directly to patient care across 16 institutes. Each thread sharpens the others: better imaging trains better AI, better biology points to better targets, and the clinic tells us which questions matter most.